Whether affected directly or indirectly, the COVID-19 pandemic has interfered in people's lives all around the world. Many treatments have been put to the test to treat patients, some with beneficial results and others not so much. With the use of published literature, this review aims to further public knowledge on how some antiviral treatments work in the human body against SARS-CoV-2 in a comparison of two widely talked about antiviral treatments: Remdesivir and convalescent plasma. The spike protein characteristic of the SARS-CoV-2 pathogen allows it to invade and infect the host cell. Convalescent plasma is fluid containing antibodies that bind to the SARS-CoV-2 pathogen, fighting against it. Remdesivir attacks the pathogen through an RNA binding site on SARS-CoV-2.